Levetiracetam for Pediatric Posttraumatic Seizure Prophylaxis
نویسندگان
چکیده
منابع مشابه
Levetiracetam for Pediatric Posttraumatic Seizure Prophylaxis
Investigators from Nationwide Children's Hospital performed an observational cohort study of early post-traumatic seizures (EPTS) among 34 children with moderate to severe traumatic brain injury (TBI) who received levetiracetam (LEV) prophylaxis following admission to their pediatric intensive care unit.
متن کاملA prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis.
BACKGROUND Brain Trauma Foundation guidelines recommend seizure prophylaxis for preventing early posttraumatic seizure (PTS). Phenytoin (PHE) is commonly used. Despite a paucity of data in traumatic brain injury, levetiracetam (LEV) has been introduced as a potential replacement, which is more costly but does not require serum monitoring. The purpose of this study was to compare the efficacy of...
متن کاملShould Levetiracetam or Phenytoin Be Used for Posttraumatic Seizure Prophylaxis? A Systematic Review of the Literature and Meta-analysis.
BACKGROUND Posttraumatic seizure (PTS) is a significant complication of traumatic brain injury (TBI). OBJECTIVE To perform a systematic review and meta-analysis to compare levetiracetam with phenytoin for seizure prophylaxis in patients diagnosed with severe TBI. METHODS An inclusive search of several electronic databases and bibliographies was conducted to identify scientific studies that ...
متن کاملRetrospective analysis of levetiracetam compared to phenytoin for seizure prophylaxis in adults with traumatic brain injury.
BACKGROUND Phenytoin is standard of care for seizure prophylaxis following traumatic brain injury (TBI). Levetiracetam, an alternative antiepileptic drug, is utilized for seizure prophylaxis despite limited data supporting its use. OBJECTIVE Our primary outcome was post-TBI seizure activity measured by electroencephalogram (EEG) for levetiracetam versus phenytoin. Secondary outcomes were leng...
متن کاملRole of Intravenous Levetiracetam in Seizure Prophylaxis of Severe Traumatic Brain Injury Patients
Traumatic brain injury (TBI) can cause seizures and the development of epilepsy. The incidence of seizures varies from 21% in patients with severe brain injuries to 50% in patients with war-related penetrating TBI. In the acute and sub-acute periods following injury, seizures can lead to increased intracranial pressure and cerebral edema, further complicating TBI management. Anticonvulsants can...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2016
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-30-3-1